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Non-destructive Analysis (NDA)

Circuit Edit (CKT)

Materials Analysis (MA)

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MA-tek FTP

Liquid-TEM by K-kit

Some samples, such as biological tissues or fluids, must receive specific treatment prior to becoming test specimens. Some important characteristics of the sample may be compromised during such treatments. In particular, particle dispersion is only meaningful when the particles are in the relevant media.The electron microscope is a vital tool for characterizing composition and morphology at the nanoscale. Most electron microscopy is conducted in a vacuum environment.

 

With the core concept of ‘simple and convenient’, K-kit solves the problem of analyzing nanoparticles in liquid. Any liquid product containing nanoparticles can be analyzed using K-Kit, which will enhance product development and manufacturing QC, thus profoundly strengthening the product’s competitive advantage.

 

K-kit is an innovative specimen holder developed by MA-tek for liquid analysis in TEM

 

 

 

Technical Concept

K-kits are sample holders designed to facilitate convenient TEM observation of liquid samples, allowing nanoobjects, aggregates, and agglomerates (NOAAs) in liquid samples to be characterized; with vacuum compatible sealing of liquids in electron-transmitting thickness, K-kits are micro reaction chambers for countless experiments in materials, chemical and biological research.

 


Compatible with all kinds of TEM holder

 

Dried on Cu grid

Dried Mode of K-kit

 

 

Liquid Sample TEM

Characterize Nano-objects, Aggregates, and Agglomerates (NOAAs) in Product’s Final Form or Relevant Media

 

Our Technology (K-kit)

Specimen kit for observing the original morphology and physical state of nanomaterials in liquid sample by TEM

 

 

(a) Wet mode:The loaded liquid sample is sealed and imaged by TEM in the native liquid environment.

(b) Thin Layer (Dry) mode:A proprietary sample preparation protocol preserves the original morphology and physical state with improved imaging resolution.

 

Click the link to get more information about K-kit:https://www.bioma-tek.com/bioma-tek/en/goods.php?act=view&no=18

 

 

Application

 

 

Nano in Products

Characterize Nano-objects, Aggregates, and Agglomerates (NOAAs) in Electronics, Cosmetics, Foods, Medical Devices, Drugs and etc…

 

 

 

 

Nano in Cosmetics

K-kit can be used for characterizing NOAAs in cosmetics in final product forms, including lotion, cream, and powder, to assess the safety risks of nanomaterials in cosmetic ingredients.

 

Goes with the emerging trend for regulatory, manufacturing, and R&D Purposes.

  • International Cooperation on Cosmetic Regulation Report (ICCR) 2012
    Characterization of Nanomaterials II – Insolubility, Biopersistence and Size Measurement in Complex Media.
  • European Union (EU) Cosmetics Regulatory (EC) No. 1223/2009
    Mandatory labeling of Nanomaterials as ingredients in Cosmetics (effective 2013/07/11)
  • United States Food and Drug Administration Guidance (US FDA) 2012
    Guidance for Industry - Safety of Nanomaterials in Cosmetic Products

 

  • Definitive:Direct observation in product’s final form or relevant media, minimizing artifacts.
  • Quantitative:Image-based statistical analysis of aggregation/agglomeration and particle concentration.
  • Comprehensive:All physicochemical characterization requirements can be addressed.

 

 

 

 

 

Nano in Foods

Characterize nanomaterials in food additives & product’s final form.

 

Goes with the emerging trend for regulatory, manufacturing, and R&D Purposes.

  • European Food Safety Authority Guidance (ESFA) 2011
    Guidance on the Risk Assessment of the Application of Nanoscience and Nanotechnologies in Food and Feed Chain.
  • European Union (EU) Food Regulatory (EC) No. 1169/2011
    Mandatory labeling of Nanomaterials as ingredients in Foods (effective 2014/12/13).
  • United States Food and Drug Administration Guidance (US FDA) 2012
    Guidance for Industry: Assessing the Effects of Significant Manufacturing Process Changes,Including Emerging Technologies, on the Safety and Regulatory Status of Food Ingredients and Food Contact Substances, Including Food Ingredients that are Color Additives.

 

 

 

 

Nano in Pharmaceuticals

Comprehensive Physicochemical Characterization of Materials in Relevant Media - in vitro and in vivo by TEM.

 

  • Direct Observation in Relevant Media

 

  • With Advanced Sample Preparation Techniques

 

Click the link to get more information about K-kit:https://www.bioma-tek.com/bioma-tek/en/goods.php?act=view&no=20